| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a9748cba32d11b97792642258e164062 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-246
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 |
| filingDate |
2006-07-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_06eb4a3e66e52880cd11ce64080d807f |
| publicationDate |
2009-10-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2009269362-A1 |
| titleOfInvention |
Method for Controlling Immunodominance |
| abstract |
Methods for controlling immunodominance are described. These methods are carried out by altering the kinetic stability of a complex between a class II Major Histocompatibility Complex (MHC) molecule and the epitope for which immunodominance is to be altered. Alterations that increase the kinetic stability of the epitope: class II MHC complex confer immunodominance upon the epitope. Methods are also described for stimulating an immune response in an organism to a specific epitope by administering to the organism a form of that epitope which has been altered to be immunodominant. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10172936-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2011153532-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9408906-B2 |
| priorityDate |
2005-07-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |