http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009246249-A1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f11611973e332b7f5c793d99636c131c |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-16 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61F2-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B05D7-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B05D7-14 |
filingDate | 2009-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_33a1503bcb538d531c557220844e63c4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cfde58de0d534ce73fde4ba868f705f9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_156adc92268d218bf30238897308d59f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1579a99e1ad64fb955add78e97789c81 |
publicationDate | 2009-10-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-2009246249-A1 |
titleOfInvention | Coating compositions having improved performance |
abstract | The presently disclosed subject matter provides compositions comprising a first substrate-binding domain (a peptide or a polymer) having binding affinity for a tissue or a medical device, a second substrate-binding domain having binding affinity for a target molecule, and the target molecule. In some embodiments, the first and second substrate-binding domains are covalently linked. The first and second substrate-binding domains are covalently coupled to at least one hydrophobic interaction tag, negatively charged interaction tag, or positively charged interaction tag. When the substrate-binding domains are combined and coated onto the tissue or medical device, the hydrophobic interaction tags interact with each other and the charged interaction tags interact with the oppositely charged interaction tags or the oppositely charged substrate binding polymers, to form a macromolecular network of non-covalently coupled substrate-binding domains to load the target molecule onto the tissue or medical device. |
priorityDate | 2008-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 660.