Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f35c1a935a6193e6ebabbac1340a0aa5 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-195 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-63 |
filingDate |
2007-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_26efcc1a608b48a06e8c1db7d0a61ff5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e1209e2ac7e91311078e027e83782d77 |
publicationDate |
2009-09-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2009233850-A1 |
titleOfInvention |
CVN-12p1: a recombinant allosteric lectin antagonist of HIV-1 envelope gp120 interactions |
abstract |
The invention provides a recombinant multi-functional chimera of CVN and 12p1. Chimeras of CVN and 12p1 present a model for targeting gp120 at two discrete sites, by two different modes of inhibition and with increasing potency versus either component alone. A chimera of the invention combines the high affinity suppression of viral activity by CVN with the allosteric suppression of viral envelope binding to both CD4 and co-receptor by 12p1. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9667514-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9703863-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8396871-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10467252-B1 |
priorityDate |
2006-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |