| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5bc5292a07e34d16eb1d033a16d3aec3 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2320-32 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-111
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6455
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-0041
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5146 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-11
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C321-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-00 |
| filingDate |
2009-02-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5e6d86c5a9bd4fb38fc6483f36894865
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_704ef8c80a19552f9710fae08fcefa21 |
| publicationDate |
2009-09-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2009233365-A1 |
| titleOfInvention |
Arginine-conjugated bioreducible poly(disulfide amine) polymers for gene delivery systems |
| abstract |
An arginine-grafted bioreducible poly(disulfide amine) (“ABP”) as a reagent for efficient and nontoxic gene delivery is described. ABP forms positively charged nano-particles of less than 200 nm with plasmid DNA. ABP is biodegraded under reducing conditions, such as the cytoplasm. ABP exhibits much higher transfection efficiency than polyethyleneimine in mammalian cells and exhibits no cytotoxicity. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9907861-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014185975-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8153155-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20150114260-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101577893-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2013109983-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010010067-A1 |
| priorityDate |
2008-02-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |