| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_61777999ebda3499b9a413195bab7ef7 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6809
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6827 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate |
2005-04-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b08fa526850085afb5770059f6166cc3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_867643f158bb200ba91053842c4f44ff
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_70f0432c82b6e9a434db39abb0927e01 |
| publicationDate |
2009-08-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2009215034-A1 |
| titleOfInvention |
Method for selectively detecting subsets of nucleic acid molecules |
| abstract |
Method for selectively detecting nucleic acid molecules comprising structural aberrations that are capable of being convented into nicks comprising generating linear nucleic acids from a selected nucleic acid substrate population; denaturing and re-annealing the linear nucleic acids to form nucleic acid duplexes; masking the nucleic acid duplex termini and internal structural aberrations with a masking component; modifying the masked nucleic acids by introducing nicks therein using at least an enzyme possessing endonuclease activity: labelling the modified nucleic acids with labelled nucleotides via nucleic acid nick translation with at least an enzyme displaying a nucleic acid polymerase activity; and selecting and identifying the labelled nucleic acid. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7985546-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010151473-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010209912-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009137407-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111751540-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8076069-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11268087-B2 |
| priorityDate |
2004-04-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |