Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f98e77d1aba3a9c2fb565cc42cc7c76f |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2320-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2320-51 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-3231 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-344 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-341 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-315 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-11 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H21-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7088 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-111 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1137 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7088 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-11 |
filingDate |
2003-11-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5494927eebe71d8c716fd87e6e2d4815 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fd9d89c85fbd027725599281c2d00d98 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4fe45acededa0c4aa81f72a0e5077f93 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d7c1664e9e3d3cc21d8a969af536d72f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cad715e8830d727562a76a3e41895ed2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5e4ef8364f433381184b511c7ece427a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8c2b0c447dbe5d59146073f8902b6813 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_37c3804f3dedefe015fe5857ab83fb99 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1294d426e4933ef3cd6ea4018f43818a |
publicationDate |
2009-08-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2009209748-A1 |
titleOfInvention |
Oligonucleotides with alternating segments of locked and non-locked nucleotides |
abstract |
The present invention is directed to novel oligonucleotides with improved antisense properties. The novel oligonucleotides comprise at least one Locked Nucleic Acid (LNA) selected from beta-D-thio/amino-LNA or alpha-L-oxy/thio/amino-LNA. The oligonucleotides comprising LNA may also include DNA and/or RNA nucleotides. The present invention also provides a new class of pharmaceuticals which comprise antisense oligonucleotides and are useful in antisense therapy. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016061487-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021188611-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016040589-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016069694-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016164746-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023044094-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023003805-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3904519-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016205323-A1 |
priorityDate |
2002-11-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |