http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009203728-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_37b416a8c0d2b0f1c3d6026d932027af |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D221-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-439 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02 |
| filingDate | 2005-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a4dd1625104bbd9577e083b3669810d8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f2801ff5735bcf4d39e613071c6762c9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c2a1f769d00fd04ad7b04e4f7c96f25d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ba2605d17ad99ac2a761270c79c5f8e3 |
| publicationDate | 2009-08-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2009203728-A1 |
| titleOfInvention | Naphthalamide derivatives having antiproliferative activity |
| abstract | The invention relates to compounds for use in medicine. The compounds are of general formula (I) as disclosed herein and the pharmaceutically acceptable salts, individual isomers and mixtures of isomers thereof, wherein X, X′ and X″ are independently O or S; Z is N or P; R3 is optional and is selected from the group consisting of optionally substituted C 1-8 alkyl, optionally substituted C 2-6 alkenyl, optionally substituted C 2-6 alkynyl, optionally substituted C 1-6 alkoxy, optionally substituted C 1-6 thioalkyl, optionally substituted C 5-10 aryl, optionally substituted C 6-11 alkylaryl, optionally substituted C 1-6 alkylamino, optionally substituted C 1-6 alkylcarbonyl, optionally substituted C 1-6 alkylsulfonamino, optionally substituted (C 1 -C 6 )alkylsulfinyl, optionally substituted C 1-6 alkylcarbonylamino, optionally substituted hetero(C 4 -C 10 )aryl, hydroxyl, halogen, cyano, nitro, amino, formyl, and thiol; R 1 , R 2 , R 4 , R 5 , R 6 , R 7 , R 8 , R 9 , and R 10 are independently selected from the group consisting of hydrogen, optionally substituted C 1-8 alkyl, optionally substituted C 2-6 alkenyl, optionally substituted C 2-6 alkynyl, optionally substituted C 1-6 alkoxy, optionally substituted C 1-6 thioalkyl, optionally substituted C 5-10 aryl, optionally substituted C 6-11 alkylaryl, optionally substituted C 1-6 alkylamino, optionally substituted C 1-6 alkylcarbonyl, optionally substituted C 1-6 alkylsulfonamino, optionally substituted (C 1 -C 6 )alkylsulfinyl, optionally substituted C 1-6 alkylcarbonylamino, optionally substituted hetero(C 4 -C 10 )aryl, hydroxyl, halogen, cyano, nitro, amino, formyl, and thiol; and - - - indicates an optional double bond. |
| priorityDate | 2005-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
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