| abstract |
Disclosed herein is an isomer, enantiomer, diastereoisomer or tautomer of a compound represented by Formula I: n n n n n n n n n n or a prodrug, or a pharmaceutically acceptable salt, or labeled with a detectable label or an affinity tag thereof; wherein R 1 , R 1a , R 100 , R 100a , R 2 , R 200 , W, B, and W 1 are defined herein. Also disclosed are methods of using compounds of Formula I to treat proliferative disorders such as cancer. |