http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009181443-A1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0a26fbc85a633fe45a0f2618e337bb43 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e6f3bc1cc847389da3018104bce1a6bc |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-18 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 |
filingDate | 2009-01-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d884ebe95c3c535f7ca51ffa4890e64e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_533188c564a898dce091ce1b4b29a721 |
publicationDate | 2009-07-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-2009181443-A1 |
titleOfInvention | Identification, cloning, expression, and a purification of three novel human calcium-independent phospholipase a2 family members possessing triacylglycerol lipase and acylglycerol transacylase activities |
abstract | Isolated novel and purified and characterized phospholipase A 2 , referred to herein as calcium-independent phospholipase A 2 zeta (iPLA 2 zeta) having SEQ. ID. NO: 2 (See FIG. 1 ), and nucleic acid sequence (SEQ. ID. NO: 4), and calcium-independent phospholipase A 2 eta (iPLA 2 eta) having SEQ. ID. NO: 3 (See FIG. 1 ), and nucleic acid sequences (SEQ. ID. NO: 5). For the first time herein, these novel enzymes have been isolated and characterized and are involved in the catalysis, synthesis and hydrolysis of lipids in a living mammalian cell. Moreover, these enzymes iPLA 2 zeta and iPLA 2 eta through the process of transesterification can catalyze the net anabolic synthesis of triglycerides through a variety of metabolic precursors (e.g. monoacylglycerol, diacylglycerol and acyl CoA). |
priorityDate | 2003-12-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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