| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_31f87c170ea6e478544c388bd11bb684 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2021-7716
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2201-0221
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-66
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2021-772
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2021-773
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2021-6441 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-7703
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B5-445
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-37
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B5-0059
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6428
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-648 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61B5-00 |
| filingDate |
2007-12-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_022b13e425b3519e90fe553d995adb05
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_05c58d7c50252eff68c50488b688a40a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_32ab3c3b02945c39ac2c715ca95ca8dd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c5fccdb9dfbed468a39ccc2c1bc01271
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_53fc1e853cf0aaae6abb7ad3fb52280f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e8057c3604ad69c1163f1ad28f085507 |
| publicationDate |
2009-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2009156942-A1 |
| titleOfInvention |
Resonance Energy Transfer Based Detection of Nosocomial Infection |
| abstract |
Disclosed herein are methods and devices for detection of hospital acquired infections. Disclosed methods may be utilized for continuous in vivo monitoring of a potential infection site or for periodic in vitro monitoring of tissue or fluid from a patient and may be utilized to alert patients and/or health care providers to the presence of a pathogen at an early stage of infection. Disclosed methods utilize fluorophore pairs that optically interact with one another according to Forster resonance energy transfer (FRET) or bioluminescence resonance energy transfer (BRET) mechanism. One member of the pair or a cofactor that interacts with an enzyme to form a member of the pair may be tethered to a device by a substrate that is specific for an enzyme expressed by a targeted pathogen. Upon interaction of the enzyme with the substrate, an optically detectable signal may be altered or initiated, detection of which may then provide information as to the existence of the pathogen at the site. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2565630-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11754488-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2012268731-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9012830-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2018252555-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108351303-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10261243-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11131619-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017091609-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10677735-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10942177-B2 |
| priorityDate |
2007-12-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |