Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7b94d2715cda37c1f23e48f9f4f23422 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bcff13f8573db698307f919e6385d5c4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e4bbea82630d80aad44eb441cd881c3d |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-507 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2740-16011 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-34 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2818 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2809 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2806 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02 |
filingDate |
2008-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_072ed4d103840e5ebd587277eba8506a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_971df1289e696cc529ed4646f17fe8b6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_85ba714ab03b8dfbb649ca5dee6dd4d0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6647527348503a7cf792330603a70d78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_853d32b632609e1fdc1a306753a29f47 |
publicationDate |
2009-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2009155836-A1 |
titleOfInvention |
Methods for treating hiv infected subjects |
abstract |
Methods for inducing a population of T cells to proliferate by activating the population of T cells and stimulating an accessory molecule on the surface of the T cells with a ligand which binds the accessory molecule are described. T cell proliferation occurs in the absence of exogenous growth factors or accessory cells. T cell activation is accomplished by stimulating the T cell receptor (TCR)/CD3 complex or the CD2 surface protein. To induce proliferation of an activated population T cells, an accessory molecule on the surface of the T cells, such as CD28, is stimulated with a ligand which binds the accessory molecule. The T cell population expanded by the method of the invention can be genetically transduced and used for immunotherapy or can be used in methods of diagnosis. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10294454-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11512288-B2 |
priorityDate |
1988-11-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |