Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cd727aa2b4e6c347aadd94971881d671 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0014 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-10 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F7-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0014 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C31-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F7-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-06 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F7-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-24 |
filingDate |
2006-08-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_38ad4d124c9d9c5a3c9e04976aef727d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_580491a5d395bd62ef5d4280db2dd16f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6abca33a79a6dd2429e75de5c50fb2d4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7b927625ebb6551b944c819816006919 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a1321dbffdae8886bbae1edb0795e99d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_55c141f7234eecf7c65b3b8b276bcd7b |
publicationDate |
2009-06-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2009149554-A1 |
titleOfInvention |
Water-soluble metal alcoholate derivatives, production methods thereof, and solid gelatinous external preparations containing the same |
abstract |
The object of the present invention is to provide a production method of water-soluble silane derivatives, the separation and purification of which are easy, and the reaction for which can be conducted under an industrially practicable temperature condition (under the temperature condition of 90° C. or lower) and to provide compounds with which solid gelatinous external preparations, with excellent stability against a temperature change and against an effect of additives and with excellent usability, can be prepared. The water-soluble silane derivative could be formed by the substitution reaction of a metal alkoxide with a polyhydric alcohol under the presence of a solid catalyst. According to this production method, the separation of the catalyst from the product is very easy, and the reaction can be carried out under the temperature condition of 90° C. or lower. The obtained water-soluble metal alcoholate derivative can satisfactory solidify an aqueous formulation of an external preparation by its blending thereinto. The obtained solid gelatinous external preparation has excellent stability against a temperature change and against the effect of additives. In addition, the external preparation is easily disintegrated during use; thus the usability such as easiness to be scooped up with fingers and spreadability during application is excellent. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8518170-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8324089-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10966327-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8629294-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9657039-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10533022-B2 |
priorityDate |
2005-08-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |