| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_00865518664c9b66e60dce35c34bd4c7 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08B37-0075
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-727
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08L5-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-727
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08B37-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate |
2008-08-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_079046ad59ad547e93c2a0e032296e08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3616eebe5c090f36165f82ccb5a08b05
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8a3b2167796ea8b505064f830c024368
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4e66ee071b16864db0cf54c06be9f674
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_041292c9a445bfcd1737efe46355adca |
| publicationDate |
2009-06-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2009149424-A1 |
| titleOfInvention |
Heparin conjugates and methods |
| abstract |
Heparin conjugates and methods of making and use thereof are disclosed. An illustrative heparin conjugate includes a composition wherein a bile acid is bonded to heparin through the 3-carbon of the bile acid. A spacer may be interposed between the bile acid and the heparin. Another embodiment includes a targeting moiety bonded to the heparin-bile acid conjugate through a spacer. Another illustrative heparin conjugate includes heparin covalently bonded to a sulfonated moiety, such as a naphthalene trisulfonate residue. A method of treating cancer includes administering a heparin conjugate to an individual in need thereof. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020228206-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016070082-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2925786-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110025792-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9212233-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2022362399-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2011130697-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10702546-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109154016-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114539343-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3223859-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102985443-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9358252-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009275543-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010298260-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10016449-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9351992-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10350169-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10017585-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9387256-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2011130697-A2 |
| priorityDate |
2007-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |