Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_916075766043ce900399a4c2eee9f054 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-164 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-06 |
filingDate |
2008-12-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f98046d139c4dc3e48fd5953f3ab3012 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b22e8b8a6e54a63972fd490247371b84 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e7fe31d423f0ef22bcb323ef05a4a01b |
publicationDate |
2009-06-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2009149383-A1 |
titleOfInvention |
Compositions and methods for facilitating heme-iron export from cells |
abstract |
The invention provides a high affinity heme-binding agent, which can be provided in the form of a pharmaceutical composition that includes, optionally, a pharmaceutically acceptable carrier. The heme-binding agent can be used in a method of facilitating heme-iron export from a cell. The method comprises contacting a cell with a high affinity heme-binding agent. Also provided is a method of treating a disorder associated with excess iron in cells in a subject. The method comprises administering to the subject an effective amount of the composition of the invention. The subject is typically a mammal, most typically a human or veterinary subject. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012050874-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2760992-A4 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012050874-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2014249087-A1 |
priorityDate |
2007-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |