| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f2ecd9ea24dae4cfdf98a7928666c469
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e30d56a69785bd92bc954e7bbab28e12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_145594414f901f98ac7ac343c7b87bc1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_726a409ab6abcc464719b2d97dc4d54b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_01a12a63374f07e5186f188c551902b2 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-70546
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-23
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2848
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-64
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-574
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-59
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-565 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-23
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-59
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-565
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 |
| filingDate |
2008-01-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3fe920412fa4555fd72beabf5258c087
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4ade696fdaf488122690761bf1439534
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_794b2ea504ab3bcadf5e48477370d0f5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6418f442181a92fafe4f9251093d3d87
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9d93698dd94df030ba642a2f28c00270 |
| publicationDate |
2009-06-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2009148459-A1 |
| titleOfInvention |
Prevention or Treatment of Cancer Using Integrin alphavbeta3 Antagonists in Combination with Other Agents |
| abstract |
The present invention relates to methods and compositions designed for the treatment, management or prevention of cancer. The methods of the invention comprise the administration of an effective amount of one or more antagonists of Integrin α V β 3 alone or in combination with the administration of an effective amount of one or more other agents useful for cancer therapy. The invention also provides pharmaceutical compositions comprising one or more antagonists of Integrin α V β 3 and/or one or more other agents useful for cancer therapy. In particular, the invention is directed to methods of treatment and prevention of cancer by the administration of a therapeutically or prophylactically effective amount of one or more antagonists of Integrin α V β 3 alone or in combination with standard and experimental therapies for treatment or prevention of cancer. Also included are methods for screening for epitope-specific Integrin α V β 3 antagonists which can be used according to the methods of the invention. In addition, methods for facilitating the use of Integrin α V β 3 antagonists in the analysis of Integrin α V β 3 expression in biopsies of animal model and clinical study samples are also contemplated. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9645155-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8993261-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8420348-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9234007-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-102304832-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2013016297-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10022420-B2 |
| priorityDate |
2002-03-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |