| abstract |
A method of predicting an effect of a test chemical on living organisms, which comprises:n a step of administering a plurality of chemicals whose effects on living organisms are known, to respective chemical dosed groups, administering a test chemical to a test chemical dosed group, collecting proteins from each group after a definite period of time, separating the proteins by two-dimensional gel electrophoresis, measuring the signal intensities of spots of the proteins and modified proteins formed therefrom, and calculating a signal intensity ratio of at least two spots, and a step of comparing the signal intensity ratio of test chemical dosed group with the signal intensity ratio of each chemical dosed group. |