http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009130212-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a81d3c3b7664fcf585e36eaf1eba61ed |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-145 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-192 |
| filingDate | 2007-05-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_47979cc89cafafbdc3c5e872a60599a2 |
| publicationDate | 2009-05-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2009130212-A1 |
| titleOfInvention | Composition and improved method for preparation of small particles |
| abstract | The present invention relates to a novel method of loading drug molecules into small pores, along with the composition so produced. In a preferred embodiment, the drug is dissolved in a suitable solvent (which may or may not be biocompatible), and the solution is allowed to move into the pores of solid matrixes by, e.g., capillary action, optionally under the influence of pressure or vacuum. The drug is then precipitated in the pores by evaporating the solvent faster than the drug can diffuse out of the pores, which leaves solid drug particles that are not larger than the pore. Since the pore radii in solid pharmaceutical matrixes can be as small as several nanometers, the drug particle size range includes particles that are much smaller than those produced using current methods. The solvent may be a pure material, a combination of solvents, a combination of liquids and surfactants, or a supercritical fluid with or without surfactants. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2015153613-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016138503-A1 |
| priorityDate | 2006-05-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 96.