| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_db8acd71f5994544bda6df3f27a3f51e |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2533-90
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2503-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2533-54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2533-52 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0693 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12M1-00 |
| filingDate |
2008-10-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c5f8e5e92f084c3cb5c7fced036d4ab8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_351a5bc35b7ead8e9767d48cef33a492 |
| publicationDate |
2009-05-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2009117653-A1 |
| titleOfInvention |
Method and apparatus for evaluating therapeutics on cancer stem cells |
| abstract |
Embodiments provide cell culture methods to produce a 3-D model assembly that mimics in vitro the microenvironment of human bone marrow, where cells occupy distinct niches. Methods and apparatuses are provided for the efficient testing of cancer, including malignant hematopoietic cancers and metastatic spread to the bone marrow of solid tumors, and of other diseases of the blood and bone marrow. Methods and apparatuses are further provided in embodiments for the investigation of bone marrow cell biological characteristics and for the testing of therapeutics for nonmalignant diseases of the blood and bone marrow. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014159707-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10329623-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10184113-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2016137986-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9958432-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11486876-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2015042450-A1 |
| priorityDate |
2007-10-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |