http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009111997-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_60551c4d219adc4b1ccb49f4c7fbd739 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1e928454484ff9413bb3d5d5f9010766 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D235-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4188 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D235-02 |
| filingDate | 2006-11-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c45659c76584684f7df0626429c50b7d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_08922430b38461ac2b126a42702daf81 |
| publicationDate | 2009-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2009111997-A1 |
| titleOfInvention | Method of Generating Amorphous Solid for Water-Insoluble Pharmaceuticals |
| abstract | The invention encompasses a method for making an amorphous solid of a water-insoluble pharmaceutical comprising: (1) dissolving the water-insoluble pharmaceutical in a water-miscible solvent, optionally with water, to make a solution; (2)(i) rapidly mixing the solution with an antisolvent, wherein the antisolvent is water, at low temperature to precipitate an amorphous solid of the water-insoluble pharmaceutical, or (ii) rapidly mixing the solution with an antisolvent, wherein the antisolvent is water, to precipitate an amorphous solid of the water-insoluble pharmaceutical and subsequently cooling to low temperature; and (3) isolating the amorphous solid of the water-insoluble pharmaceutical. In an embodiment of the invention, the rapid mixing is conducted using an impinging jet device. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110621305-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012001673-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019022784-A1 |
| priorityDate | 2005-11-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 314.