http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009111140-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b7317808024e524eea40a6c5a5ad6a22 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-1866 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-1896 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12M1-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02 |
| filingDate | 2007-03-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2ebcf4cd11f2ede0aa89a9fb8745bf7f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b924896a38127212faaf10485003aa3c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_30d5886b0c811bb30dd2a97621dcd99d |
| publicationDate | 2009-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2009111140-A1 |
| titleOfInvention | Systems and methods for cell measurement utilizing ultrashort t2* |
| abstract | The present disclosure is directed to a new technique for MR measurement of ultrashort T 2 * relaxation utilizing spin-echo acquisition. The ultrashort T 2 * relaxometry can be used for the quantification of highly concentrated iron labeled cells in cell trafficking and therapy. In an exemplary embodiment, a signal is induced by a low flip angle RF pulse. Following excitation pulse, a gradient readout is applied to form an echo. The time between the RF pulse and the center of the gradient readout is defined as TE. In tissues with highly concentrated iron labeled cells, T 2 * could be below 1 millisecond. Therefore, the signal can be decayed to a noise level with an echo time of a couple milliseconds. Because T 2 is much longer in SPIO labeled cells, the signal acquired by spin echo is much bigger than that from the gradient echo, thus avoiding the negative effects associated with the massive signal loss in the image. The ultrashort T 2 * relaxation map can then by overlaid on the regular T 2 * map to generate the final T 2 * map of the field of view. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9335394-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-102011082669-B4 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-102011082669-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2012004530-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11129851-B2 |
| priorityDate | 2006-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 30.