| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_df29e65c2a291a543bfc065fd927e2f5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_caf101da42cdd8c0a9a312eecc18fc9d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d30b11f0eeeabf8a463f931ce1a58895 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-35 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16C20-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B5-411
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B5-445
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B5-0075 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D241-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D251-26
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-445
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G06F19-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-25
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C17-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C43-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-495
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-53
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-03
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-075 |
| filingDate |
2006-01-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a1d19a2cc80974eb2a832eec5481a450
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_95032ca648c5f3bafb8eef5b77b12692
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1d899689936e21283e11c2b290d08be8 |
| publicationDate |
2009-04-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2009105260-A1 |
| titleOfInvention |
Molecules to Enhance Percutaneous Delivery and Methods for Discovery Therefor |
| abstract |
An IR spectroscopic technique provides methods for measuring the irritation potential of a formulation and to assess the ability of molecules to enhance the permeability of substances into and through skin using samples comprising stratum corneum. Molecules are screened for their performance as chemical penetration enhancers using a unique in silico procedure that may be applied iteratively in an attempt to generate molecules showing successively higher performance. Both the irritation potential and the ability of the molecule to enhance penetration are considered in the in silico approach. The invention provides specific molecules that may be used in topical or transdermal formulations to improve the delivery of actives. The structures of compounds of the invention include: Formulas (I), (II), (III), (IV), (V), (IV) and analogs thereof. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2021287764-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-7058857-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2019045165-A |
| priorityDate |
2005-02-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |