Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bfb2e45bf20f98254390fc3e49184747 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-573 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-008 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-57 |
filingDate |
2006-05-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e2d8d765018e35dc62db8865e67668dc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3af6407b765d84dde42472ac6f013666 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9bab9ea9a03a90d6b3c719890e36de12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_42668f0e011b94494d389ee39583730f |
publicationDate |
2009-04-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2009104125-A1 |
titleOfInvention |
Stable liquid desoximethasone compositions with reduced oxidized impurity |
abstract |
The present invention relates to a stable liquid formulation comprising desoximetasone, isopropyl myristate, a C 2 -C 4 alcohol and a stabilizing agent. Specifically, the present invention provides a liquid formulation comprising: a) about 0.01 wt % to about 2.5 wt % desoximetasone; b) about 10 wt % to about 70 wt % isopropyl myristate; c) about 20 wt % to about 70 wt % C 2 -C 4 alcohol; and d) a stabilizing agent selected from the group consisting of an oleaginous vehicle and a propellant, wherein the stabilizing agent is in an amount sufficient to reduce the formation of less than about 1 wt % 17-carboxy-9α-fluoro-11β-hydroxy-16a-methyl-androsta-1,4-diene-3-one under an accelerated storage condition. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019224035-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009208424-A1 |
priorityDate |
2005-05-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |