| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b6720d1c8b54c3573baacde0d0c8d99c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_eac67ca750d6aeda91f951577f4922ad
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4ef81c01e86f786d4c652977da0ad36c |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-3233
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-321
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-315
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-113 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-113 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7105 |
| filingDate |
2008-08-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0bacadc6ccd2527883fd38918588685a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7aa9c340b97a31668ec2d825697ee5c3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1749d0626b3533bb552c7714749f9e79 |
| publicationDate |
2009-04-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2009099123-A1 |
| titleOfInvention |
Antisense microRNA and uses therefor |
| abstract |
Provided herein are methods to suppress specificity protein (Sp) activity in a cell associated with a cell proliferative disease. The methods are effective to inhibit a microRNA in the cell using an antisense microRNA oligonucleotide which results in an increase in expression of a specificity protein (Sp) suppressor gene thereby inducing Sp degradation, apoptosis or growth arrest by releasing inhibitors of G2/M (Myt-1) or inhibition. Also provided are methods of treating a cancer using the antisense microRNA oligonucleotide. In addition the present invention provides antisense microRNA-27a oligonucleotides useful in the methods described herein. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8609617-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2012053229-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8957042-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2014356459-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2016122762-A1 |
| priorityDate |
2007-08-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |