Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c81d97576dbeeb2b3e24fb19792da2e1 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-11 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C40B20-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6869 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C40B50-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C40B80-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C40B40-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C335-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C40B40-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C40B40-06 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C40B40-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C40B20-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C40B50-18 |
filingDate |
2008-08-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a5f7ae5619c71845178c8cb3ba6ffaf3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7c19dbc0d7a7b1c1b0189afe8f391470 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f729afac21f226a29996feb24ad8fb9d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0bfa12b9e18b4dfc53d1cbd11230e926 |
publicationDate |
2009-04-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2009099027-A1 |
titleOfInvention |
Methods of Modifying Support Surfaces for the Immobilization of Particles and the Use of the Immobilized Particles for Analyzing Nucleic Acids |
abstract |
Methods of modifying a nucleophilic surface of a support are described. The methods involve reacting a multifunctional electrophilic reagent with nucleophilic groups on the surface of the support. The resulting electrophilic surface can be used for the covalent attachment of particles (e.g. beads) having nucleophilic functional groups. For example, nucleic acid templates with nucleophilic (e.g., amine) groups can be attached to a surface of the particles. The nucleophilic groups on the nucleic acid templates can then be used to attach the particles to the modified surface of the support. The resulting support-bound particles can be used to analyze (e.g., sequence) the nucleic acid templates on the particles. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9146248-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8173198-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3872101-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010086927-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10249038-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9591268-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10017586-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010179075-A1 |
priorityDate |
2007-08-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |