Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ffae06b19e3112b43d4bb4b66741292f |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-472 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-02 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P27-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4709 |
filingDate |
2008-09-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_007662c469a6d338cec4a3248ec5ba77 |
publicationDate |
2009-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2009087443-A1 |
titleOfInvention |
Pharmacological Adjunctive Treatment Associated with Glaucoma Filtration Surgery |
abstract |
A composition for controlling or preventing progression of glaucoma comprises a material that reduces or inhibits production of a TGF-β isoform or a chemokine or cytokine that stimulates expression of a TGF-β isoform. The material can comprise a dissociated glucocorticoid receptor agonist (“DIGRA”), a prodrug thereof, a pharmaceutically acceptable salt thereof, or a pharmaceutically acceptable ester thereof. The composition can further comprise an antagonist to TGF-β. It is administered to a patient who has undergone glaucoma filtration surgery to ensure a functioning filtering bleb following such surgery. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10111985-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10227289-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10726943-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11596710-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2010123769-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10507262-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011077270-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11083821-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10189773-B2 |
priorityDate |
2007-09-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |