| abstract |
The present invention relates to a novel pyrazolo[1,5-a]pyrimidine compound of the formula [I]: n n n n n n n n n n wherein R 1 and R 2 are the same or different and an optionally substituted aryl group etc.n Q is single bond, a methylene group or a group of the formula: —N(R Q )—, R Q is an alkyl group, Ring A is a substituted pyrazole ring fused to the adjacent pyrimidine ring having the following formula (A), (B) or (C), nn n n n n n n n n n n n R 3 and R 4 are the same or different and a hydrogen atom, a cyano group etc. n E is one of the following groups (i) to (v): n n n n n n n n n n n n n n n n R 00 is an alkyl group, Q 1 is a single bond etc., Q 2 is a single bond or an alkylene group, one of R 5 and R 6 is a hydrogen atom or an alkyl group and the other is an alkyl group etc., one of R 50 and R 60 is a hydrogen atom or an alkyl group and the other is a hydrogen atom, an alkyl group etc., R 51 is an alkyl group or an optionally substituted arylsulfonyl group, R 61 is an alkylamino group or an azido group, or a pharmaceutically acceptable salt thereof. |