| abstract |
The present invention relates, as medicaments, to the α-D-mannopyranosyl-1 phosphate derivatives of formulae I, II and III: n n n n n n n n n n (where each group R 11 to R 14 , R 21 to R 24 , R 31 to R 34 is H or an OH-protective group, and R and R′ are defined as indicated in the description), which can be used as cellular sources of Man-1 P, against the CDG-I syndrome and in particular the CDG-Ia syndrome. n The invention also relates to these derivatives as industrial products and to their method of preparation. |