http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009047700-A1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b153c183adb6fefe05ab303fe02f014b http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_61dafec25c6546bd319e1856f88b83e0 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5432 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-92 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-582 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02 |
filingDate | 2005-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6edb6edede9460c07e90c3dd23844e06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ad06e4c1edf607c9e720bd6dbd52a6f7 |
publicationDate | 2009-02-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-2009047700-A1 |
titleOfInvention | Flourescence Assay for MTP Activity |
abstract | The present invention is directed to methods for assaying microsomal triglyceride transfer protein (MTP) which are amenable to automation and high throughput screening. The assays may be used to measure MTP activity in cell and tissue homogenates as well as purified MTP. Also provided are methods of measuring levels of lipids transferred by MTP. The methods provided by the present invention have the advantages of ease, rapidity, sensitivity, avoidance of the use of radioactivity, versatility in studying different lipid transfer activities by purified and cellular MTP and the ability to measure inhibitory activity. In addition, methods of identifying compounds that modulate the lipid transfer activity of MTP are provided. Kits for measuring the lipid transfer activity of MTP as well as net transfer of lipid by MTP are provided by the present invention. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006228764-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11740235-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2011003406-A3 |
priorityDate | 2004-06-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 136.