| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d97e62338300afc0c0bfa57b698799b9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c682c345b77a187a991f3cef8673c5c4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f5c3f7688db7a0079cc107634f3d99a7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_95a54570b422bd2ee17d950e07fd3911 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-35 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-90 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-90
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-11
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-04 |
| filingDate |
2008-07-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3a1babd02842201052f77126527f46ed
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_87522069bc87b2b2a54ee4a8ee94a8c1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c3f20af7ca1f8467e78837350e7e085f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4573b4c33387a7055a057934d99bad6a |
| publicationDate |
2009-02-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2009042251-A1 |
| titleOfInvention |
Chimeric fusion protein |
| abstract |
The invention discloses the cloning, expression and uses of a chimeric fusion protein with superior chaperone and folding activities compared to the wild type chaperones. This invention relates to a chimeric fusion protein encoded by a recombinant DNA molecule comprising nucleotide sequences coding for a polypeptide binding segment of a non-human chaperone protein and nucleotide sequences coding for an FK506 binding protein (FKBP) or an FK506-binding-protein-like domain (FKBP-like domain). In particular, this invention relates to a chimeric fusion protein encoded by a recombinant DNA molecule comprising nucleotide sequences coding for a polypeptide binding segment of a non-human chaperone protein and nucleotide sequences coding for a human FKBP type peptidyl-prolyl-cis/trans isomerase (PPIase), methods of producing these chimeric fusion proteins and their uses as folding helpers in the production of other proteins and in the process of the production of vaccines or pharmaceuticals, and as folding helpers for performing immunoassays. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018161038-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11629340-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11446398-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016004024-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10316322-B2 |
| priorityDate |
2006-01-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |