http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009036647-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_dc6553d095ca5f9b401601389b95f33e |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-8114 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-02 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-435 |
filingDate | 2005-06-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_356c903279c07cb85be4daac97cf4a4f |
publicationDate | 2009-02-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-2009036647-A1 |
titleOfInvention | BITORAN WHICH IS TRYPSIN-INHIBITOR-LIKE PROTEIN DERIVED FROM BITIS ARIETANS VENOM, AND USE THEREOF AS BLOOD COAGULATION FACTOR Xa INHIBITOR |
abstract | The present invention provides a novel Kunitz-type inhibitor protein exhibiting high potency to inhibit serine protease activity of human blood coagulation factor Xa. The Kunitz-type inhibitor protein against human blood coagulation factor Xa according to the present invention isn a Kunitz-type inhibitor protein: bitoran D from Bitis arietans venom having the following amino-acid sequence I: nn n n n n n n (SEQ ID NO:1) n n n n n n SKKRP DFCYL PADDG PCRAF IPSFY YNSTS NECNT FIYGG n n n n n CYGNA NKFES MDECR KTCVA SA, n n n n n n n n n n n n n n n n n a Kunitz-type inhibitor protein: bitoran V from Bitis arietans venom having the following amino-acid sequence II: n n n n n (SEQ ID NO:2) C RQNRP DFCYL PAVEG PCRAY IRSFF YNSTS NECEK FFYGG CYGNA NKFET RDECR KTCVA SA, nor a modified protein thereof. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101391988-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9745363-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3016971-A4 |
priorityDate | 2005-06-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 194.