Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_59c6a921f33fe0adc58c2b6177184515 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-23 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 |
filingDate |
2008-07-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_de7212416e616e29e1306650c2b00baf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e3ceb838885353c5e3ac4459c4b3ad43 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3f440b920927f386b95f0ef14e6ae3b5 |
publicationDate |
2009-01-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2009028855-A1 |
titleOfInvention |
Inhibitors of akt/pkb with anti-tumor activity |
abstract |
The subject invention concerns materials and methods for inhibiting the Akt/PKB pathway. In one embodiment, a compound of the invention inhibits kinase activity and/or phosphorylation levels of Akt proteins. The subject invention also concerns methods for inhibiting or killing a cancer cell or other cell in which expression of an Akt protein is elevated or constitutively active, comprising contacting the cell with an effective amount of a compound of formula I. The subject invention also concerns methods for treating cancer or a tumor in a person or animal comprising administering all effective amount of a compound of formula I to the person or animal. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9610289-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8058289-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7842698-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10092567-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011034458-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008269227-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9717730-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114099681-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012135749-A3 |
priorityDate |
2007-07-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |