Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_34feacf0ddf2f3acee2a8c1dc7a6d25b |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-43595 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-9121 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-582 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5008 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5014 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5035 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5041 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-533 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-533 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-25 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C40B30-06 |
filingDate |
2007-10-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7723d6624ba41489c4f0c153c4c485ac http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c937e25788e540765bb7cdafba295508 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5f2f76acb2b7ad0828cb1ab5f47544d0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3a1abdf293372c6bae54e69df04dec96 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aa1627059c238dff4b78be24c532787c |
publicationDate |
2009-01-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2009023598-A1 |
titleOfInvention |
Method for extracting quantitative information relating to an influence on a cellular response |
abstract |
A method for screening a library of compounds to detect a biologically active compound that modulates intracellular translocation of a subunit of a component of an intracellular pathway affecting intracellular processes includes: culturing one or more cells containing a nucleotide sequence coding for a hybrid polypeptide comprising a luminophore linked to the subunit of the component; introducing a compound of the library of compounds into the cell culture; screening the compound to determine whether the compound modulates the intracellular translocation of the subunit of the component; measuring light emitted from the luminophore to determine a first distribution; measuring light emitted from the luminophore to determine a second distribution; computing a variation between the first distribution and the second distribution by processing the measured light, any variation is indicative that the compound is biologically active. The method is also performed with a library of compounds. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8463032-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014008222-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011176728-A1 |
priorityDate |
1997-04-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |