http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009022809-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_459549086df37b5bed0003502de7e7aa |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2886 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1635 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-16 |
| filingDate | 2005-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d6dc6e35678db69b2d90c4971865025c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5589b85d8caf3e6f4e0e45b499725c48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_083140709fadf225106eb9824b989aff http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_38eb068b7a1a62f4140dbabc7c211748 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c1cb58c5ae629e34486664c7532ef389 |
| publicationDate | 2009-01-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-2009022809-A1 |
| titleOfInvention | Stable taste masked formulations of cephalosporins |
| abstract | A stable taste masked, pharmaceutical composition comprising a plurality of coated, non-disintegrating discrete dosage units, said units comprising of a core comprising one or more cephalosporins such as cefuroxime axetil and cefpodoxime proxetil and one or more coating layers. Cefuroxime axetil is in α-crystalline and amorphous forms, where at least 30% of the Cefuroxime axetil is in the α-crystalline form, wherein the particle size distribution of the α-crystalline form being such that 100% of the particles have a particle size below 250μ. The ratio of the crystalline fraction to the amorphous fraction ranges from 0.3:0.7 to 0.99:0.01. The particle size of cefpodoxime proxetil is such that 90% of the particles are below 15μ. The process of preparation of coated, non-disintegrating pellets comprising the steps of reducing the particle size of the one or more cephalosporins, blending with the other excipients, wet granulation, extrusion, spheronization, drying and screening to obtain pellets, said pellets being further coated with one or more layers of film coating to achieve taste masking. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103919734-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8465776-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009304792-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010197571-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2013038323-A1 |
| priorityDate | 2005-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 103.