http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009018343-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2fc8c4f23758df7ed658973e2a913e38 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D263-22 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D263-22 |
filingDate | 2006-03-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5168663711b6edcb2727c218041f61d4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_16ef5171864ee520b73914e30b8e2214 |
publicationDate | 2009-01-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-2009018343-A1 |
titleOfInvention | Fluorous Oxazolidinone Chiral Auxiliary Compounds and Methods of Manufacture |
abstract | The present invention relates generally to perfluoroalkyl chiral auxiliary compounds and methods of manufacture. These compounds have the functionality to effectively support the synthesis of chiral compounds in single reactions, high-throughput parallel reactions, or combinatorial reactions The invention relates to two oxazolidinone chiral auxiliaries (1) and (2): wherein R f is a perfluoroalkyl group having the general formula (CH 2 ) x —C y F 2y+1 where x=1-5 and y=4-10 and wherein B is an unfunctionalized aryl, alkyl or arylalkyl group in a preferred embodiment, x=2 and y=6 and B is derived from unfunctionalized amino acids The amino acids may be from either the D- or L-series, and are preferably enantiomerically pure or in very high enantiomeric excess in either configuration. |
priorityDate | 2005-03-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 340.