Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_943263e27d5ad0513aefaa1f1eb04c8d http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f110dbd4bef60f29a9fb26d8de7e3832 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b4914f622ef23bd62bfd8cc3f4ddc86a http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8f953a20a05d540caa67626c3059ac5f |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4747 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-04 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-00 |
filingDate |
2006-01-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f781ebf35868066afa393c7486e5562e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_41b549d71236752cd7187c1bb9f4b738 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0ea7173db991ce3828b05ade838aa023 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_469a60536a3d1ad045dd8bd435f6e6ae |
publicationDate |
2009-01-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2009005538-A1 |
titleOfInvention |
Apoptosis-Inducing Agent for Prostate Cancer Cells |
abstract |
According to the present invention, an apoptosis-inducing agent for prostate cancer comprising REIC/Dkk-3 DNA or an REIC/Dkk-3 protein, and a therapeutic agent for prostate cancer and an agent for inhibiting prostate cancer metastasis that comprise such apoptosis-inducing agent are provided. n An apoptosis-inducing agent for prostate cancer, comprising, as an active ingredient, an REIC/Dkk-3 protein (a) or (b) or REIC/Dkk-3 DNA (c) or (d):n (a) a protein consisting of the amino acid sequence represented by SEQ ID NO: 2; (b) a protein consisting of an amino acid sequence derived from the amino acid sequence represented by SEQ ID NO: 2 by substitution or deletion of 1 or more amino acids; (c) DNA consisting of the nucleotide sequence represented by SEQ ID NO: 1; or (d) DNA that hybridizes under stringent conditions to DNA consisting of a nucleotide sequence complementary to the nucleotide sequence represented by SEQ ID NO: 1 and encodes a protein having apoptosis activity; and a therapeutic agent for prostate cancer comprising such apoptosis-inducing agent are provided |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2016176938-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/IL-260185-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8658612-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8618273-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8946173-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8614093-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11484592-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2716756-A4 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9644013-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2716756-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010173404-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011189237-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2014147917-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106497883-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9475865-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9222107-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017119499-A1 |
priorityDate |
2005-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |