Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_754bdccb63651325cc24896b7ce99ed7 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-23 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-232 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-557 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-216 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-202 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-557 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P17-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P17-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P17-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-232 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-23 |
filingDate |
2006-09-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fdfa7a7bec2f9ac19a295bd7ff86359a |
publicationDate |
2008-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2008312323-A1 |
titleOfInvention |
Inhibition of TNF-alpha-Initiated Response |
abstract |
The impact of lipoxin A 4 (LXA 4 ) and aspirin-triggered-lipoxins (ATL) was investigated in tumor necrosis factor (TNFα)-initiated neutrophil (PMN) responses in vitro and in vivo using metabolically stable LX analogs. At concentrations as low as 1-10 nM, the LXA 4 and ATL analogs each inhibited TNFα-stimulated superoxide anion generation and IL-1β release by human PMN. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008081838-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020076578-A1 |
priorityDate |
1999-03-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |