| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9be2a04d148b4dd0d9e4b7a1bece4ac9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fa8c3287e125b157c3852b9b28cee3b6 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D491-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4353
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-505
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-04 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-505
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4353
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-18 |
| filingDate |
2008-05-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8721fc74e9f670fb460223f31fc93049
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_74156c5e894a4a2aa2b2f455cab7051a |
| publicationDate |
2008-12-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2008306098-A1 |
| titleOfInvention |
Pharmacokinetics of protease inhibitors and other drugs |
| abstract |
A method for modulating at least one pharmacokinetic property of a protease inhibitor upon administration to a host is provided. One administers to the host an effective amount of a bifunctional compound of less than about 5000 daltons comprising the protease inhibitor or an active derivative thereof and a pharmacokinetic modulating moiety. The pharmacokinetic modulating moiety binds to at least one intracellular protein. The bifunctional compound has at least one modulated pharmacokinetic property upon administration to the host as compared to a free drug control that comprises the protease inhibitor. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017136708-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9109002-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11197877-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10766916-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11707474-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11712446-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11780873-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11072625-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2019510738-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11708391-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10662220-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11332491-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10519181-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10526361-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11433086-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9796745-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11066416-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11555054-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11291678-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11548908-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010284993-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9867841-B2 |
| priorityDate |
2006-11-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |