| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6791043cefd9ec30efa05a16f12a20ed
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_36e74e14c6c9778010ad3cee7064ed8d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b1fdc1b72951307d1716a7c4d986517e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f31ae2f0b4b62abb9f81750f10f3401a |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-364
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-106
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-136 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C40B40-06 |
| filingDate |
2005-03-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_694282f19bbd8610e9d0f693cf931e95
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4ab41c32c5d905930a87ea8a1df15bb1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b86f53b6ffbdbd25fec493ff9b7e8580
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e7dc46c3dccebb09e022cbdac37967b2 |
| publicationDate |
2008-12-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2008300147-A1 |
| titleOfInvention |
Detection and Treatment of Fibrotic Disorders |
| abstract |
The present invention provides a method for detecting a fibrotic disorder in a subject by: (a) providing a biological sample obtained from the subject (such as endometrium, peritoneal fluid, and/or smooth muscle cells); (b) analyzing the expression of at least one gene that is differentially expressed in the fibrotic disorder of interest; and (c) correlating the expression of the gene(s) with the presence or absence of the fibrotic disorder in the subject. The present invention also provides a method and compositions for modulating the expression of genes that are differentially expressed in fibrotic tissues, compared to normal tissues. Restoration of gene expression to levels associated with normal tissue is expected to ameliorate at least some of the symptoms of the fibrotic disorder. This method includes the step of contacting the tissue with an agent that modulates expression of one or more differentially expressed genes in the tissue. The present invention also includes arrays, such as microfluidic cards, for detecting differential gene expression in samples of fibrotic tissue. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10184124-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10662430-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9938530-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9938575-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006275747-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9963702-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8664189-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10815485-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9303259-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9340786-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10913948-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2013178376-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011020352-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007219824-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11584933-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103070875-A |
| priorityDate |
2004-03-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |