Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a998f8ffdbe80bf754a93422e166156d |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-70596 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-705 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-06 |
filingDate |
2005-02-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_266d967fd4990b3d8a1f335c566626de http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c66c843667356ba19a5d013529ebec36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ade0102909115f904a5d83770c4a8539 |
publicationDate |
2008-12-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2008299546-A1 |
titleOfInvention |
Canine Cd20 Gene |
abstract |
It is intended to clarify the CD20 amino acid sequence and its gene sequence which are essentially required in constructing an anti-CD20 antibody useful in treating animal malignant lymphoma. It is also intended to provide a method of diagnosing canine malignant lymphoma by using the gene sequence. Using monocytes in canine blood as a sample, mRNA is obtained and the full base sequence of canine CD20 gene (SEQ ID NO:2) is determined. Based on this sequence, its amino acid sequence (SEQ ID NO:1) is determined. Comparing the homologies with human and mouse CD20 genes and amino acid sequences, it is identified as canine CD20 gene. Moreover, a primer specific to the canine gene is constructed and the expression of the CD20 gene in a sample is examined, thereby giving a method of diagnosing canine B lymphocyte-origin malignant lymphoma. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11319377-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9616120-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9790280-B2 |
priorityDate |
2004-02-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |