| abstract |
The present invention relates to quinazolinones of formula (I) wherein R 1 is hal; a); b); or c); X is N or CR 8 ; R 2 is hal; nitro; C 1 -C 6 alkylcarbonyl; C 1 -C 6 alkyl or C 3 -C 6 cycloalkyl; R 3 is C 1 -C 6 alkyl; C 1 -C 6 alkoxy or amino; and wherein the further radicals have the meanings as defined in the specification, which compounds exhibit human vanilloid antagonistic activity; to processes for their production, their use as pharmaceuticals and to pharmaceutical compositions comprising them. |