Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1bddc4f8d1cb2c68028a0c1104d7fb03 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-91215 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-705 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-95 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-485 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-556 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-00 |
filingDate |
2007-05-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b1044c07a236274228ef3fb4f5b1f6bb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c75148a40256173960a4c2bae7ee40b4 |
publicationDate |
2008-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2008293073-A1 |
titleOfInvention |
Methods for Assessing CDK5 Activation and Function |
abstract |
As described herein, signaling events occurring in neurons or at neuronal synapses have been identified that involve Cdk5 and various other molecules which bind to, are activated by, and/or activate Cdk5. Of particular relevance are interactions that stimulate calpain cleavage of p35 into p25, which binds Cdk5 in pathologic states. Assays to identify modulators of these interactions are provided. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2010141710-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8699383-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8728472-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2010141710-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109553685-A |
priorityDate |
2007-05-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |