| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_686b67d962e6c9ad044240bc1c92c754
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3c1c7555d7833ac8af46c0ca61bfa2b2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_be2645b02712316f2fc179c282e58514
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ffc1bb8603365df2627dd61b5ddedac4 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2250-0068 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61F2-82
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-28 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61F2-82
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61F2-24 |
| filingDate |
2006-04-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d361639ae2004ff7e8c206ff3320b72c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bf7dd8752d9e6f57f6da4a1ad179e171
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b5d7ff6831bc8dccb79a8d374b4183ce
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d78c286728becf9b254353c436cbc2f5 |
| publicationDate |
2008-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2008288057-A1 |
| titleOfInvention |
Bioactive Stents For Type II Diabetics and Methods for Use Thereof |
| abstract |
The present invention is based on the discovery that a vascular stent or other implantable medical device can be coated with a biodegradable biocompatible polymer to which is attached a bioligand that specifically captures progenitors of endothelial cells (PECs) from the circulating blood to promote endogenous formation of healthy endothelium in Type II diabetics. In one embodiment, the bioligand is a peptide that specifically binds to an integrin receptor on PECs. The invention also provides methods for using such vascular stents and other implantable devices to promote vascular healing in Type II diabetics, for example following mechanical intervention. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2015005893-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9517203-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9102830-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103110985-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11202762-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2014018909-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102151185-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9283241-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10888531-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102085125-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8652504-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9510810-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9963549-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9896544-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9873764-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9873765-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2014018849-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006286064-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10434071-B2 |
| priorityDate |
2004-04-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |