| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_47054da942b228608c4fe1c2dbec1fdb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5207b2135384ecf97c3ffaa8db4cdac4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1b5eaa25a963e90610ce9ad8d55c1656
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8507202fd88d32cfd6929e35df740e66 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-093 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-661
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-127
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-003 |
| filingDate |
2005-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c8928b9fe7912cbdad6952327c44e749
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f8b81c35b237a69f932a480cfde3d356
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ad2383b9f1746d3d346991b74cc12cfe
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3ec69e604f52dd66deb36d9bfe2cf7fb |
| publicationDate |
2008-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2008286351-A1 |
| titleOfInvention |
Pegylated Cardiolipin Analogs, Methods of Synthesis, and Uses Thereof |
| abstract |
The invention provides synthetic methods for PEGylated cardiolipins with varying linkers. The methods can be employed to prepare PEGylated cardiolipin with different fatty acid and/or alkyl chain length with or without unsaturation. The PEGylated cardiolipin, prepared by the present methods, can be incorporated into liposomes that can also include active agents such as hydrophilic or hydrophobic drugs for the treatment of human and animal diseases. In addition, the PEGylated cardiolipin can be incorporated into liposomes that include compounds for therapeutic and diagnostic imaging. The use of such liposomes with PEGylated cardiolipin prolongs the period of liposomal circulation without disrupting the lipid bilayer. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10561611-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9895313-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009232730-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009281054-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10736845-B2 |
| priorityDate |
2004-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |