| abstract |
Ophthalmically acceptable compositions used in arresting the development of cataracts or macular degeneration comprising a pharmaceutically acceptable carrier or diluent and a compound having the formula: n n n n n n n n n n where R 1 and R 2 are, independently, H or C 1 to C 3 alkyl; n R 3 and R 4 are, independently C 1 to C 3 alkyl; and n where R 1 and R 2 , taken together, or R 3 and R 4 , taken together, or both may be cycloalkyl; n R 5 is H, OH, or C 1 to C 6 alkyl; n R 6 is or C 1 to C 6 alkyl, alkenyl, alkynyl, or substituted alkyl or alkenyl; n R 7 is C 1 to C 6 alkyl, alkenyl, alkynyl, or substituted alkyl or alkenyl n or where R 6 and R 7 , or R 5 , R 6 and R 7 , taken together, form a carbocycle or heterocycle having from 3 to 7 atoms in the ring. |