Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_882726efdf925151461e6d6d86b77e3f http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d7086b98b2986f0de4bb57e356cd2400 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9371cc47f8363f3773bb2e7dc92e90c4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2a85e240882ee14ac8fdf4f5997e30d7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e566f60c33f84eeb8a4b1b2eceaeba5e http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_77d1ea96c034a9d9c00fc65923877b75 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-522 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2035-11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12R2001-42 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-205 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-255 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-42 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-112 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-31 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-255 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-76 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-12 |
filingDate |
2007-02-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ab0d760b1ebb1dd3be98df75dd23088a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dbeb50f04a65de4b5a3bed74f2389809 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5f0f1eed3476592d6b1d258980208a75 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2d2c5eecf67491e9509995f7a124ec2d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0cabf11d3519a8589736c0f142b29a40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d3f68c2672dbcaa8f2d1a23c3e08e088 |
publicationDate |
2008-11-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-2008274139-A1 |
titleOfInvention |
Attenuated microorganisms for the treatment of infection |
abstract |
The present invention pertains to a Salmonella microorganism having an attenuating mutation which disrupts the expression of a gene located within the Spi2 pathogenicity island, and an auxotrophic mutation. The microorganism therefore has a double mutation which helps prevent reactivity of the microorganism while maintaining the effectiveness of the microorganism to elicit an immune response. The present invention also pertains to vaccine compositions and methods for treating and preventing a Salmonella infection in a patient. |
priorityDate |
1999-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |