| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1c359427bc1d1030c55e6a027c3124d3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e103f038e0adbb252645aad82a31f6b1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c3ec1f4be30d241266bc9d6d6e0cfffc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0e23ba1b5b317f7180284aa061a27a20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3018052c18f4963f673f5c8c5676ed8a |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-64
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2740-16122
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2740-16134
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-60
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-622
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-55572
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-55555
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-55561
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-55594
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-55577
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-53
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-545
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-54 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-21
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-12 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 |
| filingDate |
2005-06-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1941089e093f2ecaf3826a7cf4ae41b7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aa7e1181339dbe1ce7fa8fb83309e887
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_39a5dd0d10c0ce425641fe5f9fe03432
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2160ec89bf7a1464771f509fdca511a4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9ae0ea7544222450f3e17ec98d83e8ea |
| publicationDate |
2008-11-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2008274134-A1 |
| titleOfInvention |
Hiv-1 Neutralizing Antibodies Elicited By Trimeric Hiv-1 Envelope Glycoprotein Complex |
| abstract |
This invention provides methods for eliciting an immune response in a subject comprising administering to the subject as part of a regimen (i) more than one dose of a nucleic acid prime, and (ii) more than one dose of a protein boost composition, wherein each dose of the nucleic acid prime is administered to the subject at a first predefined interval and each dose of the protein boost composition is administered to the subject at a second predefined interval, and wherein the protein boost composition comprises a prophylactically or therapeutically effective dose of (a) a trimeric HIV-1 gp140 protein complex, or (b) a superparamagnetic particle and a trimeric HIV-1 gp140 protein complex so affixed thereto as to permit recognition of the complex by a subject's immune system. The invention also provides methods for prophylactically or therapeutically treating HIV-1 infection in a subject. The invention further provides uses of a nucleic acid prime and a protein boost composition for the manufacture of separate coadministerable medicaments to be administered to a subject. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10124060-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2014212458-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012003234-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9738688-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10058604-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2016015802-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10869921-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9675687-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11690906-B2 |
| priorityDate |
2004-06-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |