| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_362d7df142655613551c77e74b6366de |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-90 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-803
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-80 |
| filingDate |
2005-10-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_246d4be83a9a9bdc3adee1cd347a70ed
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_99098a10f027ba5a0553b7eec5df852d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_41f54cc028588d2a11c600e33cf23091
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e70f807bd99128df50a9cf8ea5835bbb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a540def311358929c51bbb3032e98f15 |
| publicationDate |
2008-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2008262239-A1 |
| titleOfInvention |
Process for Producing Enantiomer of Amlodipine in High Optical Purity |
| abstract |
The present invention relates to a process for preparation of optically pure (S)-amlodipine-L-hemitartrate DMF solvate comprising the steps of treating (R,S) amlodipine base with L-tartaric acid in the presence of dimethyl formamide and a co-solvent. The invention also relates to a process for converting (R) or (S)-amlopidine-L-hemitartrate DMF solvate into their besylates without isolating free chiral amlopidine base after solution. |
| priorityDate |
2004-10-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |