| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1a341c6d71ef7c4ffb900306369c5ce3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e60c310edc110c3fe163f33e50403fa4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4471cb5e5f3841893dcd446776544111 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-12 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0664
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K6-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0652
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0654 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-12 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-077
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00 |
| filingDate |
2006-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_991f96c83cc00f98ed8b5ee4d4de90d9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_925a43c39c0d218ed91eb686e0d602d4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f1fd4bd6ed32ca9f54b51f03ea15c052 |
| publicationDate |
2008-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2008253999-A1 |
| titleOfInvention |
Methods For Differentiating Stem Cells and Uses Thereof in the Treatment of Dental Conditions |
| abstract |
The present invention relates to a method for propagating and/or differentiating mammalian cells, the method comprising exposing or co-culturing mammalian cells with one or more of periodontal ligament tissue, periodontal ligament proteins or factors derived from periodontal ligament tissue, to obtain cells having PDL characteristics and fulfilling at least one of the following:n i) show periodontal characteristics as evidenced with Von Kossa method in which calcium phosphate deposits are stained brown to black, ii) show increased osteopontin and osteocalcin and at the same time decreased bone sialoprotein (bone sialoprotein II or BSP), iii) are capable of being implanted to repair and/or regenerate periodontal tissue, iv) are capable of repairing disorders such as paradentitis also called paradentosis, or periodontitis by healing of the gum line towards the teeth, and v) are accepted by the host without significant immune reaction or cell rejection. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9962237-B2 |
| priorityDate |
2005-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |