http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008234489-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7ed7f635ad2edcd05703bf9803bbf3c1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8fc7c8722f8b1eca854f81c366cc652f |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F15-065 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F15-06 |
filingDate | 2007-03-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_afd5d631cc629bff2b9bd131691b01b7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8dad54984459646bc7569c708953e441 |
publicationDate | 2008-09-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-2008234489-A1 |
titleOfInvention | Method of synthesis of the sodium salt of N-acetyl-L-cysteinylcobalamin |
abstract | The invention provides a method for preparing the sodium salt of the novel thiol derivative of vitamin B 12 , N-acetyl-L-cysteinylcobalamin (Na[NACCbl]). The method involves carrying out the reaction in aqueous solvent with a relatively small excess of ligand reactant, specifically from one to less than four molar equivalents. The cobalamin derivative formed is precipitated from the aqueous solvent, preferably by the addition of a precipitate inducing solvent. This provides a product in acceptable purity without the need for an additional chromatographic purification step. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11309959-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10819441-B2 |
priorityDate | 2007-03-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 115.