| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_77b882994730b56387bf64207ab816e7 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D275-03
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C323-60 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C231-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D275-03 |
| filingDate |
2006-04-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0c17d4272382f3621e5358ce474faf2b |
| publicationDate |
2008-09-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-2008227986-A1 |
| titleOfInvention |
Preparation of N-Substituted Isothiazolinone Derivatives |
| abstract |
Provided is a process for the preparation of an N-substituted isothiazolinone derivative having the general formula (I), comprising reacting N-substituted 3-mercaptopropionamides of formula (II) or N,N′-bis-substituted 3,3′-dithiodipropionamides of formula (III) with sulfuryl chloride in the absence of solvents. Also provided is a process for the preparation of a compound having the general formula (III), comprising reacting a methyl ester of formula (IV) with an amine of formula (V) in a solvent of methanol. As no addition solvent is used in the process of the invention, the cost of manufacturing and pollution to the environment can be reduced. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2013171676-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106588810-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103570642-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103804251-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8507691-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103804251-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103570642-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010234613-A1 |
| priorityDate |
2006-04-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |